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  • The Food and Drug Administration, FDA, has approved the drug Vivitrol to the treatment of opioid dependence as outlined by a news release by them on 10-12-2010.

    Using two separate drugs to shed pounds can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the those who go through it you ought to err to the side of caution and allow FDA do its job and demand some research be done so that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on the medications.

    Researchers discovered that participants investing in this drug to get a year, dropped excess weight within 4 weeks and have kept the extra weight off throughout the 56 weeks with the study. Contrave is really a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of multiple active ingredient, which may make them more potent and safer.

    Combo-pilling is the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills has become popular may be the fact that since right now there aren't long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be authorized by the FDA.

    Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug can also raise hypertension and heartbeat, and must not be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure level and heartrate and must not used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.

    Approving a drug using this many potentially lethal unwanted side effects is inconsistent with the mission statement of the FDA. The power from the drug manufacturing lobby is blatantly evident inside approval of countless drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety in the US.

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